Magnetic Catalyst CdFe2O4: Direct Conversion of Thiols into Antibacterial Sulfonamides

Document Type : Original Research

Authors

1 Department of Plant Physiology and Systems Biology, Delhi University.

2 Department of Chemical Sciences and Technologies, Delhi University.

Abstract

Sulfonamides are a significant class of molecules with a diverse array of biological functions. Numerous sulfonamide conjugate pharmacological actions have been reported during the past few decades. Additionally, a large number of lead compounds with sulfonamide activity are being tested in clinical settings to treat a range of illnesses. For these reasons, research in organic synthesis has long been focused on developing an effective method for the synthesis of sulfonamides. Over the years, a great deal of research has been done to show how successful the N-alkylation and sulfonylation processes are in producing sulfonamide. In the present work, cadmium ferrite (CdFe2O4) nanoparticles were synthesized by a simple thermal decomposition method and its application in the synthesis of sulfonamides was investigated. With the help of X-ray diffraction, scanning electron microscopy, and Fourier transform infrared spectroscopy, prepared nanoparticles were identified. The average particle crystal size was collected and found to be approximately 21 nm using XRD studies. This catalyst can be easily separated and recycled for 6 consecutive periods.

Graphical Abstract

Magnetic Catalyst CdFe2O4: Direct Conversion of Thiols into Antibacterial Sulfonamides

Keywords